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HA155

Chemical Structure : HA155

CAS No.: 1229652-22-5

HA155 (Autotaxin Inhibitor IV)

Catalog No.: PC-38464Not For Human Use, Lab Use Only.

HA155 is a potent, boronic acid-based autotaxin (ATX) inhibitor with IC50 of 5.7 nM, also used for conjugation to icodextrin.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

HA155 is a potent, boronic acid-based autotaxin (ATX) inhibitor with IC50 of 5.7 nM, also used for conjugation to icodextrin.

Physicochemical Properties

M.Wt 463.286
Formula C24H19BFNO5S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

B-[4-[[4-[[3-[(4-fluorophenyl)methyl]-2,4-dioxo-5-thiazolidinylidene]methyl]phenoxy]methyl]phenyl]-boronic acid

References

1. Albers HM, et al. J Med Chem. 2011 Jul 14;54(13):4619-26.

2. Fisher N, et al. J Med Chem. 2018 Sep 13;61(17):7942-7951.

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