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HDAC1 inhibitor L17h

Chemical Structure : HDAC1 inhibitor L17h

CAS No.:

HDAC1 inhibitor L17h

Catalog No.: PC-28562Not For Human Use, Lab Use Only.

HDAC inhibitor L17h is a potent and highly selective HDAC1 inhibitor, transcriptionally upregulates acyl-CoA synthetase long-chain family member 4 (ACSL4) expression, potentiates ferroptosis with arachidonic acid in ESCC.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

HDAC inhibitor L17h is a potent and highly selective HDAC1 inhibitor, transcriptionally upregulates acyl-CoA synthetase long-chain family member 4 (ACSL4) expression, potentiates ferroptosis with arachidonic acid in ESCC.

Physicochemical Properties

M.Wt 462.35
Formula C24H20BrN3O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(E)-3-(4-((2-(4-bromophenyl)-5-methyl-1H-benzo[d]imidazol-1-yl)methyl)phenyl)-N-hydroxyacrylamide

References

1. Meng Liu, et al. J Med Chem. 2026 Oct 8;69(19):22611-22636.

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