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HDAC8 inhibitor Compound 3

Chemical Structure : HDAC8 inhibitor Compound 3

CAS No.: 1318791-62-6

HDAC8 inhibitor Compound 3

Catalog No.: PC-27746Not For Human Use, Lab Use Only.

HDAC8 inhibitor Compound 3 is a potent and selective HDAC8 inhibitor with IC50 of 200 nM, does not inhibit HDAC1, HDAC2, HDAC6.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

HDAC8 inhibitor Compound 3 is a potent and selective HDAC8 inhibitor with IC50 of 200 nM, does not inhibit HDAC1, HDAC2, HDAC6.

Physicochemical Properties

M.Wt 407.85
Formula C20H20ClF2N3O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-2-amino-3-(3-chlorophenyl)-1-(4-(2,5-difluorobenzoyl)piperazin-1-yl)propan-1-one

References

1. Lewis Whitehead, et al. Bioorg Med Chem. 2011 Aug 1;19(15):4626-34.

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