HF51116 | CXCR4 antagonist | Probechem Biochemicals

Chemical Structure : HF51116

Catalog No.: PC-26821Not For Human Use, Lab Use Only.

HF51116 is a potent small molecule CXCR4 antagonist with binding IC50 of 12 nM, potently mobilizes hematopoietic stem cells (HSCs) in vivo.

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Biological Activity

HF51116 is a potent small molecule CXCR4 antagonist with binding IC50 of 12 nM, potently mobilizes hematopoietic stem cells (HSCs) in vivo.

M.Wt	522.74
Formula	C29H46N8O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Pentanamide, 5-[(aminoiminomethyl)amino]-N-[[4-[[[3-(cyclohexylamino)propyl]amino]methyl]phenyl]methyl]-2-[(2-pyridinylmethyl)amino]-, (2R)-

1. Fang X, et al. Stem Cell Res Ther. 2021 Jan 7;12(1):17.

2. Fang X, et al. Eur J Med Chem. 2022 Mar 5;231:114150.