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HIF2α-IN-1

Chemical Structure : HIF2α-IN-1

CAS No.: 1799948-06-3

HIF2α-IN-1

Catalog No.: PC-45759Not For Human Use, Lab Use Only.

A potent HIF-2α inhibitor with IC50 of <500 nM in HIF-2α scintillation proximity assay. .

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Biological Activity

A potent HIF-2α inhibitor with IC50 of <500 nM in HIF-2α scintillation proximity assay.

Physicochemical Properties

M.Wt 405.2961
Formula C16H8F5NO4S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Benzonitrile, 3-[[(3R)-4-(difluoromethyl)-2,2-difluoro-2,3-dihydro-3-hydroxy-1,1-dioxidobenzo[b]thien-5-yl]oxy]-5-fluoro-

References

1. Bruick Richard Keith, et al. From PCT Int. Appl. (2016), WO 2016057242 A1 20160414.

2. Dixon Darryl David, et al. From PCT Int. Appl. (2015), WO 2015095048 A1 20150625.

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