HOIPIN-1 (JTP-0819958, HOIP inhibitor-1) | HOIP inhibitor

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Chemical Structure : HOIPIN-1

CAS No.:

HOIPIN-1 (JTP-0819958;HOIP inhibitor-1)

Catalog No.: PC-35958Not For Human Use, Lab Use Only.

HOIPIN-1 (JTP-0819958, HOIP inhibitor-1) is a chemical inhibitor of linear ubiquitin chain assembly complex (LUBAC, IC50=2.8 uM), specifically generates Met1-linked linear ubiquitin chains through the ubiquitin ligase activity in HOIP, and activates the NF-kB pathway..

Packing	Price	Stock
5 mg	$58	In stock
10 mg	$88	In stock
25 mg	$138	In stock
50 mg	$218	In stock
100 mg		Get quote

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

HOIPIN-1 (JTP-0819958, HOIP inhibitor-1) is a chemical inhibitor of linear ubiquitin chain assembly complex (LUBAC, IC50=2.8 uM), specifically generates Met1-linked linear ubiquitin chains through the ubiquitin ligase activity in HOIP, and activates the NF-kB pathway.

Physicochemical Properties

M.Wt	304.277
Formula	C17H13NaO4
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Sodium (E)-2-(3-(2-methoxyphenyl)-3-oxoprop-1-en-1-yl)benzoate

References

1. Katsuya K, et al. Biochem Biophys Res Commun. 2019 Jan 2. pii: S0006-291X(18)32846-8.

2. Katsuya K, et al. SLAS Discov. 2018 Dec;23(10):1018-1029.

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HOIPIN-1 (JTP-0819958;HOIP inhibitor-1)

Biological Activity

Physicochemical Properties

References

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