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I-229

Chemical Structure : I-229

CAS No.: 1801903-15-0

I-229 (I 229)

Catalog No.: PC-20374Not For Human Use, Lab Use Only.

I-229 is a potent and selective inhibitor of Vps34.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    I-229 is a potent and selective inhibitor of Vps34.

    Physicochemical Properties

    M.Wt 502.92
    Formula C22H17ClF2N6O2S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N-(6-chloro-4-methyl-2'-((2-methylpyrimidin-4-yl)amino)-[3,4'-bipyridin]-5-yl)-2,4-difluorobenzenesulfonamide

    References

    1. Dennis X Hu, et al. J Med Chem. 2022 Sep 8;65(17):11500-11512.

    2. Patent WO2018144791 A1.

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