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Chemical Structure : IDI-6273
Catalog No.: PC-70339Not For Human Use, Lab Use Only.
IDI-6273 is a potent, mutant-selective PfDHODH inhibitor with IC50 of 210 nM for 3D7 E182D PfDHODH.
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IDI-6273 is a potent, mutant-selective PfDHODH inhibitor with IC50 of 210 nM for 3D7 E182D PfDHODH.
IDI-6273 displays 10.95-fold more active against 3D7 E182D than 3D7.
IDI-6273 does not yield resistant parasites with a combination of Genz-669178.
| M.Wt | 341.835 | |
| Formula | C20H20ClNO2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Lukens AK, e tal. Proc Natl Acad Sci U S A. 2014 Jan 14;111(2):799-804.
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