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IDO-IN-1

Chemical Structure : IDO-IN-1

CAS No.: 914638-30-5

IDO-IN-1

Catalog No.: PC-46003Not For Human Use, Lab Use Only.

A potent, competitive indoleamine 2,3-dioxygenase (IDO) inhibitor with Hela IC50 of 19 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

A potent, competitive indoleamine 2,3-dioxygenase (IDO) inhibitor with Hela IC50 of 19 nM; decreases kynurenine levels by >50% in plasma and inhibits B16-GM-CSF tumor growth in a dose dependent fashion.

Skin Cancer

Preclinical

Physicochemical Properties

M.Wt 316.0866
Formula C9H7BrFN5O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 682 mg/mL

Chemical Name/SMILES

1,2,5-Oxadiazole-3-carboximidamide, 4-amino-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-

References

1. Yue EW, et al. J Med Chem. 2009 Dec 10;52(23):7364-7.

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