IDPU

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Chemical Structure : IDPU

Catalog No.: PC-26034Not For Human Use, Lab Use Only.

IDPU is a high potent, selective Adenosine A2A receptor (A2AR) antagonist with Ki of 0.0038 nM, has 737-fold selectivity over A1R.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

IDPU is a high potent, selective Adenosine A2A receptor (A2AR) antagonist with Ki of 0.0038 nM, has 737-fold selectivity over A1R.
IDPU attenuates haloperidol induced Parkinson like symptoms in rats.
IDPU successfully restores hypo-locomotion induced by haloperidol and NECA.
IDPU also displays protective effect against oxidative stress induced by chronic haloperidol treatment in rats.

Physicochemical Properties

M.Wt	284.36
Formula	C9H12N6OS2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(7-imino-3-propyl-2-thioxo-3,7-dihydrothiazolo[4,5-d]pyrimidin-6(2H)-yl)urea

References

1. Kumari N, et al. Neurosci Lett. 2017 Apr 24;647:53-60.

2. Kumari N, et al. Neurosci Lett. 2018 May 14;675:74-82.

3. Luthra PM, et al. Bioorg Med Chem Lett. 2010 Feb 1;20(3):1214-8.

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IDPU

Biological Activity

Physicochemical Properties

References

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