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You are here:Home-Chemical Inhibitors & Agonists-Membrane Transporter/Ion Channel-iGluR-IEM-1925
IEM-1925

Chemical Structure : IEM-1925

CAS No.: 258282-23-4

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IEM-1925 (IEM-1925 bromide, IEM1925)

Catalog No.: PC-27571Not For Human Use, Lab Use Only.

IEM-1925 is a selective antagonist of GluR2-lacking AMPA receptors (AMPAR) with KD of 1.1 uM (−80 mV), >100-fold selective over GluR2-containing AMPAR.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

IEM-1925 is a selective antagonist of GluR2-lacking AMPA receptors (AMPAR) with KD of 1.1 uM (−80 mV), has >100-fold selectivity over GluR2-containing AMPAR.

Physicochemical Properties

M.Wt 422.25
Formula C17H30Br2N2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1,5-Pentanediamine, N1-(1-phenylcyclohexyl)-, hydrobromide (1:2)

References

1. Tikhonov DB, et al. Br J Pharmacol. 2000 Jan;129(2):265-74.

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