IID432 | T. cruzi Topo II inhibitor | Probechem Biochemicals

Chemical Structure : IID432

IID432 (IID-432)

Catalog No.: PC-25928Not For Human Use, Lab Use Only.

IID432 (IID-432) is a highly potent inhibitor of Trypanosoma cruzi topoisomerase II (T. cruzi Topo II), shows potent activity against T. cruzi with EC50 of 8 nM.

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Biological Activity

IID432 (IID-432) is a highly potent inhibitor of Trypanosoma cruzi topoisomerase II (T. cruzi Topo II), shows potent activity against T. cruzi with EC50 of 8 nM.

Physicochemical Properties

M.Wt	361.41
Formula	C19H19N7O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-2-(3-cyano-1H-1,2,4-triazol-1-yl)-N-(1-(2-methylquinolin-6-yl)pyrrolidin-3-yl)acetamide

References

1. René O, et al. J Med Chem. 2026 Jan 7. doi: 10.1021/acs.jmedchem.5c02459.

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IID432 (IID-432)

Biological Activity

Physicochemical Properties

References

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