You are here:Home-Chemical Inhibitors & Agonists-Metabolic Enzyme/Protease-IMPDH- IMPDH2-IN-5
 IMPDH2-IN-5

Chemical Structure : IMPDH2-IN-5

CAS No.: 2119603-25-5

IMPDH2-IN-5

Catalog No.: PC-70215Not For Human Use, Lab Use Only.

A potent, selective IMPDH2 inhibitor that covalently binds to Cys140 with IC50 of 620 nM (inhibition of NO production).

Packing Price Stock Quantity

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC)

Biological Activity

A potent, selective IMPDH2 inhibitor that covalently binds to Cys140 with IC50 of 620 nM (inhibition of NO production); a Sappanone A derivative.

Physicochemical Properties

M.Wt 302.257
Formula C16H11FO5
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(E)-3-(3,4-dihydroxybenzylidene)-5-fluoro-7-hydroxychroman-4-one

References

1. Liao LX, et al. Proc Natl Acad Sci U S A. 2017 Jul 18;114(29):E5986-E5994.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: