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IN-1233 phosphate

Chemical Structure : IN-1233 phosphate

CAS No.: 1093953-38-8

IN-1233 phosphate (IN1233;IN 1233)

Catalog No.: PC-61448Not For Human Use, Lab Use Only.

A potent and selective TGF-βRI (ALK5) inhibitor with IC50 of 34 nM, prevents tissue hyperplasia in the rat urethra or common iliac artery..

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

A potent and selective TGF-βRI (ALK5) inhibitor with IC50 of 34 nM, prevents tissue hyperplasia in the rat urethra or common iliac artery.

Physicochemical Properties

M.Wt 517.482
Formula C26H24N5O5P
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-((4-(6-methylpyridin-2-yl)-5-(quinolin-6-yl)-1H-imidazol-2-yl)methyl)benzamide phosphate

References

1. Kim JH, et al. Radiology, May 2013 Volume 267, Issue 2, doi.org/10.1148/radiol.12120361

2. Kim JH, et al. Radiology. 2010 Apr;255(1):75-82.

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