Chemical Structure : IOX2
CAS No.: 931398-72-0
Catalog No.: PC-28710Not For Human Use, Lab Use Only.
IOX2 is a hypoxia-mimicking compound and specific prolyl hydroxylase-2 (PHD2) inhibitor with IC50 of 22 nM, promotes articular chondrocyte differentiation, regulates platelet function and arterial thrombosis by upregulating HIF-1α expression and inhibiting ROS production.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $88 | In stock | |
| 25 mg | $148 | In stock | |
| 50 mg | $248 | In stock | |
| 100 mg | Get quote |
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IOX2 is a hypoxia-mimicking compound and specific prolyl hydroxylase-2 (PHD2) inhibitor with IC50 of 22 nM, promotes articular chondrocyte differentiation, regulates platelet function and arterial thrombosis by upregulating HIF-1α expression and inhibiting ROS production.
| M.Wt | 352.35 | |
| Formula | C19H16N2O5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
2-(1-Benzyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamido)acetic acid |
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1. Sen A, et al. PLoS One. 2013 Nov 11;8(11):e78684.
2. Cheng S, et al. Sci Rep. 2017 Mar 28;7:45408.
3. Deppe J, et al. Arch Toxicol. 2016 May;90(5):1141-50.

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