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Chemical Structure : IPG7236
Catalog No.: PC-20372Not For Human Use, Lab Use Only.
IPG7236 (IPG 7236) is a potent and selective CCR8 antagonist with chemotaxis IC50 of 33.8 nM.
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IPG7236 (IPG 7236) is a potent and selective CCR8 antagonist with chemotaxis IC50 of 33.8 nM.
IPG7236 demonstrated an anti-cancer effect via modulating Treg and cytotoxic T (CD8+ T) cells.
IPG7236 alone or in combination with PD-1 antibody exhibited significant tumor suppression effects in the mouse xenograft model of human breast cancer.
| M.Wt | 429.58 | |
| Formula | C23H31N3O3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Yong Wu, et al. J Med Chem. 2023 Mar 29. doi: 10.1021/acs.jmedchem.3c00030.
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