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IS-741

Chemical Structure : IS-741

CAS No.: 141283-87-6

IS-741 (Fuzapladib;IS741)

Catalog No.: PC-36093Not For Human Use, Lab Use Only.

IS-741 (Fuzapladib, IS741) is a synthetic anti-inflammatory agent that shows inhibitory effect on cytosolic phospholipase A2 (cPLA2)..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

IS-741 (Fuzapladib, IS741) is a synthetic anti-inflammatory agent that shows inhibitory effect on cytosolic phospholipase A2 (cPLA2).

Physicochemical Properties

M.Wt 379.398
Formula C15H20F3N3O3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-[2-(ethanesulfonamido)-5-(trifluoromethyl)pyridin-3-yl]cyclohexanecarboxamide

References

1. Yotsuya S, et al. Digestion. 1999;60 Suppl 1:34-9.

2. Yamauchi J, et al. Digestion. 1999;60 Suppl 1:40-6.

3. Kimura H, et al. Chem Pharm Bull (Tokyo). 1995 Oct;43(10):1696-700.

4. Kaku T, et al. Pancreas. 2007 Apr;34(3):299-309.

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