ISS840 | STAT1 inhibitor | Probechem Biochemicals

Chemical Structure : ISS840

Catalog No.: PC-28221Not For Human Use, Lab Use Only.

ISS840 is a isoform-selective, peptidomimetic inhibitor of STAT1 homo-dimerization with IC50 of 31 uM, >15-fold selectivity over STAT3.

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Biological Activity

ISS840 is a isoform-selective, peptidomimetic inhibitor of STAT1 homo-dimerization with IC50 of 31 uM, >15-fold selectivity over STAT3.

M.Wt	608.59
Formula	C30H33N4O8P
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(4-Cyanobenzoyl)-O-phosphono-L-tyrosyl-N-(3-methoxyphenyl)-L-leucinamide

1. Gunning PT, et al. Bioorg Med Chem Lett. 2007 Apr 1;17(7):1875-8.