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Chemical Structure : Inarigivir
CAS No.: 475650-36-3
Catalog No.: PC-60083Not For Human Use, Lab Use Only.
Inarigivir (ORI-9020, SB-9000) is a dinucleotide that activates RIG-I and NOD2, induces interferon mediated antiviral immune responses.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $228 | In stock | |
| 10 mg | $368 | In stock | |
| 25 mg | $558 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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Inarigivir (ORI-9020, SB-9000) is a dinucleotide that activates RIG-I and NOD2, induces interferon mediated antiviral immune responses.
Inarigivir shows broad-spectrum antiviral activity against RNA viruses including HCV, norovirus, RSV and influenza, and also demonstrates activity HBV in vitro and in vivo.
Inarigivir is a novel agonist of innate immunity.
Inarigivir is the activite componet of Inarigivir soproxil (SB-9200).
| M.Wt | 587.5008 | |
| Formula | C20H26N7O10PS | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
O-(((2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl) O-((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-(hydroxymethyl)-4-methoxytetrahydrofuran-3-yl) S-hydrogen phosphorothioate |
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1. Korolowicz KE, et al. PLoS One. 2016 Aug 23;11(8):e0161313.
2. Suresh M, et al. PLoS One. 2017 Jan 5;12(1):e0169631.
3. Jones M, et al. J Med Virol. 2017 Sep;89(9):1620-1628.
4. Iyer RP, et al. Antimicrob Agents Chemother. 2004 Jun;48(6):2318-20.
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