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Chemical Structure : Indiplon
CAS No.: 325715-02-4
Catalog No.: PC-45592Not For Human Use, Lab Use Only.
A potent GABAA receptor positive allosteric modulator that acts at the benzodiazepine site (Ki values are 1.2 and 1.7 nM in rat frontal cortex and cerebellum respectively).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $79.2 | In stock | |
| 50 mg | $248 | In stock |
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A potent GABAA receptor positive allosteric modulator that acts at the benzodiazepine site (Ki values are 1.2 and 1.7 nM in rat frontal cortex and cerebellum respectively); potentiates the GABA-activated chloride current in recombinant GABA(A) receptors in a dose-dependent and reversible manner in 293 cells, 10-fold selective for α1 subunit-containing receptors over GABA(A) receptors containing α2, α3, or α5 subunits.
Sleep Disorder
Phase 3 Clinical
| M.Wt | 376.4316 | |
| Formula | C20H16N4O2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
Acetamide, N-methyl-N-[3-[3-(2-thienylcarbonyl)pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]- |
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1. Lankford A. Neuropsychiatr Dis Treat. 2007 Dec;3(6):765-73.
2. Marrs JC. Ann Pharmacother. 2008 Jul;42(7):1070-9.
3. Petroski RE, et al. J Pharmacol Exp Ther. 2006 Apr;317(1):369-77.
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