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Chemical Structure : Inh2-B1
Catalog No.: PC-61783Not For Human Use, Lab Use Only.
Inh2-B1 (STK1 inhibitor B1) is a novel specific S aureus Ser/Thr protein kinase (STK1) inhibitor with IC50 of 49 uM, directly binds to ATP-binding catalytic domain.
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Inh2-B1 (STK1 inhibitor B1) is a novel specific S aureus Ser/Thr protein kinase (STK1) inhibitor with IC50 of 49 uM, directly binds to ATP-binding catalytic domain.
Inh2-B1 exhibits in vitro growth inhibition of MRSA, and in vivo protection in mice against the lethal MRSA challenge.
Inh2-B1 down-regulates cell wall hydrolase genes and disrupts the biofilm formation of MRSA.
| M.Wt | 411.45 | |
| Formula | C19H13N3O4S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Kant S, et al. Sci Rep. 2017 Jul 11;7(1):5067.
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