Integrin-IN-27 |CAS:593274-97-6 Probechem Biochemicals

Chemical Structure : Integrin-IN-27

Integrin-IN-27 (integrin αvβ3 antagonist)

Catalog No.: PC-45511Not For Human Use, Lab Use Only.

Integrin-IN-27 is a potent integrin αvβ3 antagonist with IC50 of 18 nM.

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Biological Activity

Integrin-IN-27 is a potent integrin αvβ3 antagonist with IC50 of 18 nM.
Integrin-IN-27 could be conjugated to paclitaxel for selective delivery to alphavbeta3 positive metastatic cancer cells.

Physicochemical Properties

M.Wt	444.4394
Formula	C24H20N4O5
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	Benzoic acid, 3-[2-[[1-[2-[(4-methylphenyl)amino]-2-oxoethyl]-2,5-dioxo-4-imidazolidinylidene]methyl]-1H-pyrrol-1-yl]-

References

1. Dayam R, et al. J Med Chem. 2006 Jul 27;49(15):4526-34.

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Integrin-IN-27 (integrin αvβ3 antagonist)

Biological Activity

Physicochemical Properties

References

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