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Inupadenant

Chemical Structure : Inupadenant

CAS No.: 2246607-08-7

Inupadenant (EOS-850, EOS100850)

Catalog No.: PC-38365Not For Human Use, Lab Use Only.

Inupadenant (EOS-850, EOS100850) is a non brain-penetrant, potent and highly selective small molecule antagonist of adenosine A2a receptor (A2AR), shows activity at the high adenosine concentrations found in tumors.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Inupadenant (EOS-850, EOS100850) is a non brain-penetrant, potent and highly selective small molecule antagonist of adenosine A2a receptor (A2AR), shows activity at the high adenosine concentrations found in tumors.

Physicochemical Properties

M.Wt 604.652
Formula C25H26F2N8O4S2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-5-amino-3-(2-(4-(2,4-difluoro-5-(2-(methylsulfinyl)ethoxy)phenyl)piperazin-1-yl)ethyl)-8-(furan-2-yl)thiazolo[5,4-e][1,2,4]triazolo[1,5-c]pyrimidin-2(3H)-one

References

1. Laurence Buisseret, et al. Journal of Clinical Oncology, Volume 39, Issue 15_suppl.

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