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Chemical Structure : Ipragliflozin
CAS No.: 761423-87-4
Catalog No.: PC-44115Not For Human Use, Lab Use Only.
A highly potent and selective SGLT2 inhibitor with IC50 of 14 nM for hSGLT2.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $368 | In stock | |
| 50 mg | $1200 | In stock | |
| 100 mg | $1680 | In stock |
Bulk size, bulk discount!
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A highly potent and selective SGLT2 inhibitor with IC50 of 14 nM for hSGLT2; shows 254-fold selectivity over hSGLT1; reduces blood glucose levels in a dose-dependent manner in diabetic models KK-A(y) mice and STZ rats.
Diabetes
Approved
| M.Wt | 404.4518 | |
| Formula | C21H21FO5S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
D-Glucitol, 1,5-anhydro-1-C-[3-(benzo[b]thien-2-ylmethyl)-4-fluorophenyl]-, (1S)- |
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1. Imamura M, et al. Bioorg Med Chem. 2012 May 15;20(10):3263-79.
2. Tahara A, et al. J Pharmacol Sci. 2012;120(1):36-44.
3. Tahara A, et al. Eur J Pharmacol. 2013 Sep 5;715(1-3):246-55.
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