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Irsenontrine

Chemical Structure : Irsenontrine

CAS No.: 1429509-82-9

Irsenontrine (E2027)

Catalog No.: PC-38401Not For Human Use, Lab Use Only.

Irsenontrine (E2027) is a potent, selective and orally active phosphodiesterase 9 (PDE9) inhibitor, reduces the degradation of cyclic GMP (cGMP) which is critical to signal transmission among cells, and helps maintain the concentration of cGMP in the brain.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Irsenontrine (E2027) is a potent, selective and orally active phosphodiesterase 9 (PDE9) inhibitor, reduces the degradation of cyclic GMP (cGMP) which is critical to signal transmission among cells, and helps maintain the concentration of cGMP in the brain.

Physicochemical Properties

M.Wt 390.443
Formula C22H22N4O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-7-(2-methoxy-3,5-dimethylpyridin-4-yl)-1-(tetrahydrofuran-3-yl)-1,5-dihydro-4H-pyrazolo[4,3-c]quinolin-4-one

References

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