Isopomiferin

Chemical Structure : Isopomiferin

Catalog No.: PC-21524Not For Human Use, Lab Use Only.

Isopomiferin is a prenylated isoflavonoid, collapses the tumor checkpoint module (TCM) and suppresses both MYCN and TEAD4 in MYCN-amplified NBL cells.

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Biological Activity

Isopomiferin is a prenylated isoflavonoid, collapses the tumor checkpoint module (TCM) and suppresses both MYCN and TEAD4 in MYCN-amplified NBL cells.
Isopomiferin inhibited casein kinase 2 (CK2) in cells.
Isopomiferin inhibited MYC and MYCN in NBL and lung cancer cells.

Physicochemical Properties

M.Wt	420.46
Formula	C25H24O6
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	11-(3,4-dihydroxyphenyl)-2,2,6,6-tetramethyl-3,4-dihydro-2H,6H,12H-dipyrano[2,3-f:2',3'-h]chromen-12-one

References

1. Stokes ME, et al. Cell Chem Biol. 2023 Dec 6:S2451-9456(23)00422-1.

2. Robles S, et al. Curr Drug Discov Technol. 2017;14(3):156-168.

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Isopomiferin

Biological Activity

Physicochemical Properties

References

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