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Chemical Structure : JHU-083
Catalog No.: PC-35603Not For Human Use, Lab Use Only.
JHU-083 is an orally available prodrug of the glutaminase inhibitor 6-diazo-5-oxo-L-norleucine (DON), blocks glutaminase activity in brain CD11b+ cells and prevents depression-associated behaviors induced by chronic social defeat stress..
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JHU-083 is an orally available prodrug of the glutaminase inhibitor 6-diazo-5-oxo-L-norleucine (DON), blocks glutaminase activity in brain CD11b+ cells and prevents depression-associated behaviors induced by chronic social defeat stress.
| M.Wt | 312.37 | |
| Formula | C14H24N4O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Zhu X, et al. Neuropsychopharmacology. 2018 Aug 13. doi: 10.1038/s41386-018-0177-7.
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