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Chemical Structure : JJ-450
Catalog No.: PC-49173Not For Human Use, Lab Use Only.
JJ-450 is a novel analogue of IMTPPE and direct and specific inhibitor of androgen receptor (AR) transcriptional activity, blocks AR recruitment to androgen-responsive elements and suppresses AR target gene expression.
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JJ-450 is a novel analogue of IMTPPE and direct and specific inhibitor of androgen receptor (AR) transcriptional activity, blocks AR recruitment to androgen-responsive elements and suppresses AR target gene expression.
JJ-450 also inhibits ARv7 transcriptional activity and its target gene expression.
| M.Wt | 372.868 | |
| Formula | C21H22ClFN2O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Yang Z, et al. Mol Cancer Ther. 2020 Jan;19(1):75-88.
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