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Chemical Structure : JMV 2959
Catalog No.: PC-61828Not For Human Use, Lab Use Only.
JMV 2959 (AEZS-123) is a potent ghrelin receptor (GHS-R1A) antaognist with binding IC50 of 32 nM.
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JMV 2959 (AEZS-123) is a potent ghrelin receptor (GHS-R1A) antaognist with binding IC50 of 32 nM; suppresses ghrelin-induced and fasting-induced food intake at the level of the central nervous system, attenuates the NMDAR antagonist, phencyclidine-induced impairments in prepulse inhibition in rats.
| M.Wt | 508.626 | |
| Formula | C30H32N6O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Salomé N, et al. Eur J Pharmacol. 2009 Jun 10;612(1-3):167-73.
2. Landgren S, et al. Addict Biol. 2012 Jan;17(1):86-94.
3. Engel JA, et al. Psychopharmacology (Berl). 2015 Dec;232(23):4285-92.
4. Moulin A, et al. Amino Acids. 2013 Feb;44(2):301-14.
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