JNJ-3790339 | DGKα inhibitor | Probechem Biochemicals

Chemical Structure : JNJ-3790339

JNJ-3790339 (JNJ 3790339)

Catalog No.: PC-38842Not For Human Use, Lab Use Only.

JNJ-3790339 is a potent and selective inhibitor of diacylglycerol kinase α (DGKα), demonstrates similar cytotoxicity in GBM and melanoma cells as ritanserin.

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Biological Activity

JNJ-3790339 is a potent and selective inhibitor of diacylglycerol kinase α (DGKα), demonstrates similar cytotoxicity in GBM and melanoma cells as ritanserin.

Physicochemical Properties

M.Wt	483.674
Formula	C30H33N3OS
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	6-(2-(4-(di-p-tolylmethylene)piperidin-1-yl)ethyl)-3,7-dimethyl-5H-thiazolo[3,2-a]pyrimidin-5-one

References

1. Mitchell E Granade, et al. Biochem Pharmacol. 2022 Mar;197:114908.

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JNJ-3790339 (JNJ 3790339)

Biological Activity

Physicochemical Properties

References

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