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JPC-3210

Chemical Structure : JPC-3210

CAS No.: 1609655-35-7

JPC-3210 (JPC3210)

Catalog No.: PC-62611Not For Human Use, Lab Use Only.

JPC-3210 is a potent antimalarial agent with IC50 of 2.5-19 nM, remains activity against multidrug-resistant Plasmodium falciparum lines with little cytotoxicity in mammalian cell lines.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

JPC-3210 is a potent antimalarial agent with IC50 of 2.5-19 nM, remains activity against multidrug-resistant Plasmodium falciparum lines with little cytotoxicity in mammalian cell lines; exhibits longer plasma elimination half-life, and excellent in vivo efficacy against murine malaria.

Physicochemical Properties

M.Wt 398.446
Formula C21H26F4N2O
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-(tert-butyl)-2-((tert-butylamino)methyl)-6-(5-fluoro-6-(trifluoromethyl)pyridin-3-yl)phenol

References

1. Chavchich M, et al. Antimicrob Agents Chemother. 2016 Apr 22;60(5):3115-8.

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