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JPE1375

Chemical Structure : JPE1375

CAS No.: 1254036-23-1

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JPE1375 (JPE-1375, Hoo-Phe-Orn-Pro-hle-Pff-Phe-NH2)

Catalog No.: PC-72001Not For Human Use, Lab Use Only.

JPE1375 (JPE-1375) is a potent, peptidomimetic C5a receptor (Ca5R) antagonist with IC50 of 39 nM.

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5 mg $118 In stock
10 mg $188 In stock
25 mg $328 In stock
50 mg $528 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

JPE1375 (JPE-1375) is a potent, peptidomimetic C5a receptor (Ca5R) antagonist with IC50 of 39 nM.
JPE1375 inhibits neutrophil influx in the RPAR in mice.

Physicochemical Properties

M.Wt 955.08
Formula C49H63FN10O9
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Hoo-Phe-Orn-Pro-hle-Pf-Phe-NH2

References

1. Schnatbaum K, et al. Bioorg Med Chem Lett. 2006 Oct 1;16(19):5088-92.

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