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Chemical Structure : JTE-151
Catalog No.: PC-20043Not For Human Use, Lab Use Only.
JTE-151 (JTE151) is a potent selective RORγ antagonist with EC50 of 14 nM, acts by suppressing overactive immune response through inhibition of RORγ related to the activation of Th17 cells.
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JTE-151 (JTE151) is a potent selective RORγ antagonist with EC50 of 14 nM, acts by suppressing overactive immune response through inhibition of RORγ related to the activation of Th17 cells.
| M.Wt | 499.99 | |
| Formula | C26H30ClN3O5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Masayuki Kotoku, et al. J Med Chem. 2019 Mar 14;62(5):2837-2842.
2. Nadim S Shaikh, et al. Bioorg Med Chem Lett. 2019 Aug 15;29(16):2208-2217.
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