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JVW-1009

Chemical Structure : JVW-1009

CAS No.: 2089059-30-1

JVW-1009 (JVW 1009;JVW1009)

Catalog No.: PC-61101Not For Human Use, Lab Use Only.

A small molecule sigma receptor ligand with Ki of 96 and 70 nM for sigma 1 and sigma 2, respectively.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

JVW-1009 is a small molecule sigma receptor ligand with Ki of 96 and 70 nM for sigma 1 and sigma 2, respectively.
JVW-1009 reduces neurodegeneration in C. elegans model of amyloid precursor protein-mediated neurodegeneration.

Physicochemical Properties

M.Wt 340.47
Formula C24H24N2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(1R,5R)-2-benzyl-N-phenyl-2,3,4,5-tetrahydro-1H-1,5-methanobenzo[c]azepin-8-amine

References

1. Yi B, et al. J Neurochem. 2017 Feb;140(4):561-575.

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