Chemical Structure : JWG-071
CAS No.:
2250323-50-1
JWG-071
(JWG071)
Catalog No. : PC-72141Not For Human Use, Lab Use Only.
JWG-071 is a selective Erk5 inhibitor (IC50<20 nM) with reduced Brd4/BET inhibitory activity.
Packing Price Stock Quantity 5 mg $78 In stock 0 1 2 3 4 5 10 mg $118 In stock 0 1 2 3 4 5 25 mg $198 In stock 0 1 2 3 4 5 50 mg $338 In stock 0 1 2 3 4 5 100 mg Get quote 0 1 2 3 4 5
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-7214101
Biological Activity
JWG-071 is a selective ERK5 inhibitor (IC50<20 nM) with reduced Brd4/BET inhibitory activity.
Physicochemical Properties
M.Wt
612.779
Formula
C34H44N8O3
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
11-(sec-Butyl)-2-((2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl)phenyl)amino)-5-methyl-5,11-dihydro-6H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-one
References
1. Ignazia Tusa, et al. Oncogene
2. Charles A C Williams, et al. Cell Rep
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