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JX225

Chemical Structure : JX225

CAS No.: 424816-38-6

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JX225 (JX-225)

Catalog No.: PC-27192Not For Human Use, Lab Use Only.

JX225 is a potent, high-affinity inhibitor of neutral amino acid transporter B0AT1 (SLC6A19) with IC50 of 0.07 uM in FLIPR assays, and 0.44 uM in radioactive L-leucine uptake assays.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

JX225 is a potent, high-affinity inhibitor of neutral amino acid transporter B0AT1 (SLC6A19) with IC50 of 0.07 uM in FLIPR assays, and 0.44 uM in radioactive L-leucine uptake assays.

Physicochemical Properties

M.Wt 286.17
Formula C12H16BrNO2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-(4-bromo-3-methylphenoxy)-N-propylacetamide

References

1. Xu J, et al. Nat Commun. 2024 Aug 22;15(1):7224.

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