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Chemical Structure : JZP-430
CAS No.: 1672691-74-5
Catalog No.: PC-20129Not For Human Use, Lab Use Only.
JZP-430 (JZP430) is potent, selective and irreversible inhibitor of α/β-hydrolase domain 6 (ABHD6) with IC50 of 44 nM (hABHD6), 230-fold selectivity over FAAH and lysosomal acid lipase (LAL).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $178 | In stock | |
| 10 mg | $268 | In stock | |
| 25 mg | $478 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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JZP-430 (JZP430) is potent, selective and irreversible inhibitor of α/β-hydrolase domain 6 (ABHD6) with IC50 of 44 nM (hABHD6), 230-fold selectivity over FAAH and lysosomal acid lipase (LAL).
JZP-430 is highly selective for ABHD6 over the other detectable brain serine hydrolases, including FAAH, MAGL and ABHD12.
| M.Wt | 354.47 | |
| Formula | C16H26N4O3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
4-morpholino-1,2,5-thiadiazol-3-yl cyclooctyl(methyl)carbamate |
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1. Jayendra Z Patel, et al. ChemMedChem. 2015 Feb;10(2):253-65.
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