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Jun9-88-6R

Chemical Structure : Jun9-88-6R

CAS No.:

Jun9-88-6R

Catalog No.: PC-72517Not For Human Use, Lab Use Only.

Jun9-88-6R is a potent, selective, covalent SARS-CoV-2 Mpro inhibitor with IC50 of 0.08 uM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Jun9-88-6R is a potent, selective, covalent SARS-CoV-2 Mpro inhibitor with IC50 of 0.08 uM.
Jun9-88-6R is highly selective toward Mpro and does not inhibit the host calpain I, cathepsins B, K, L, caspase-3, and trypsin.
Jun9-88-6R inhibited SARS-CoV-2 replication in Vero E6 cells with IC50 of 0.58 uM.

Physicochemical Properties

M.Wt 686.242
Formula C29H24Br3N3O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Month
Shipping
Solubility

Chemical Name/SMILES

References

1. Chunlong Ma, et al. J Am Chem Soc. 2021 Dec 15;143(49):20697-20709.

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