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Juniferdin

Chemical Structure : Juniferdin

CAS No.: 74724-29-1

Juniferdin

Catalog No.: PC-62113Not For Human Use, Lab Use Only.

Juniferdin is a small molecule, potent Protein disulfide isomerase (PDI) inhibitor with IC50 of 156 nM, inhibits PDI-mediated reduction of HIV-1 envelope glycoprotein gp120.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Juniferdin is a small molecule, potent Protein disulfide isomerase (PDI) inhibitor with IC50 of 156 nM, inhibits PDI-mediated reduction of HIV-1 envelope glycoprotein gp120; significantly reduces the replication of influenza A and B viruses in MDCK and A549 cells.

Physicochemical Properties

M.Wt 358.478
Formula C22H30O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-Hydroxybenzoic acid 2,5,5,9-tetramethyl-4-hydroxy-2,9-cycloundecadien-1-yl ester

References

1. Khan MM, et al. ACS Chem Biol. 2011 Mar 18;6(3):245-51.

2. Kim Y,et al. Virus Res. 2018 Jan 31;247:26-33.

3. Khan MM, et al. Oncol Res. 2011;19(10-11):445-53.

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