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KBP-5074

Chemical Structure : KBP-5074

CAS No.: 1359969-26-8

KBP-5074 (KBP5074;KBP 5074)

Catalog No.: PC-35939Not For Human Use, Lab Use Only.

KBP-5074 (KBP5074) is a novel non-steroidal, highly selective mineralocorticoid receptor antagonist for the treatment of hypertensive chronic kidney disease..

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

KBP-5074 (KBP5074) is a novel non-steroidal, highly selective mineralocorticoid receptor antagonist for the treatment of hypertensive chronic kidney disease.

Other Indication

Phase 2 Clinical

Physicochemical Properties

M.Wt 504.031
Formula C28H30ClN5O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-chloro-4-((3R,3aR)-3-cyclopentyl-7-(4-hydroxypiperidine-1-carbonyl)-3,3a,4,5-tetrahydro-2H-pyrazolo[3,4-f]quinolin-2-yl)benzonitrile

References

1. Granberg K, et al. J Med Chem. 2018 Dec 31. doi: 10.1021/acs.jmedchem.8b01523.

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