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Chemical Structure : KC7F2
CAS No.: 927822-86-4
Catalog No.: PC-45555Not For Human Use, Lab Use Only.
KC7F2 is a small molecule HIF-1α translation inhibitor with IC50 of 20 uM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 25 mg | $198 | In stock | |
| 100 mg | $488 | In stock | |
| 200 mg | Get quote | ||
| 1 g | Get quote |
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KC7F2 is a small molecule HIF-1α translation inhibitor with IC50 of 20 uM.
KC7F2 prevents the activation of HIF-target genes such as CA IX, MMP2, Endothelin 1, and Enolase 1.
KC7F2 down regulates of HIF-1α protein synthesis by suppression of the phosphorylation of 4EBP1 and p70S6K.
| M.Wt | 570.3812 | |
| Formula | C16H16Cl4N2O4S4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 32 mg/mL |
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| Chemical Name/SMILES |
Benzenesulfonamide, N,N'-(dithiodi-2,1-ethanediyl)bis[2,5-dichloro- |
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1. Narita T, et al. Clin Cancer Res. 2009 Oct 1;15(19):6128-36.
2. Guan G, et al. Cancer Lett. 2015 Feb 1;357(1):254-64.
3. Cammarata PR, et al. Mol Vis. 2015 Sep 1;21:1024-35.
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