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Chemical Structure : KDS2010
Catalog No.: PC-36146Not For Human Use, Lab Use Only.
KDS2010 (KDS-2010, KDS 2010) is a potent, highly selective, reversible Monoamine oxidase-B (MAO-B) inhibitor with IC50 of 7.6 nM.
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KDS2010 (KDS-2010, KDS 2010) is a potent, highly selective, reversible Monoamine oxidase-B (MAO-B) inhibitor with IC50 of 7.6 nM.
KDS2010 displays 12,500-fold selectivity over MAO-A.
KDS2010 shows a marked enantiomer selectivity (eightfold selectivity) over the (R)-isomer.
KDS2010 significantly ameliorates the impairments in spike probability, learning, and memory in APP/PS1 mice, but not by selegiline, also reverses spatial learning and memory impairments in the Morris water maze test.
| M.Wt | 322.331 | |
| Formula | C17H17F3N2O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Park JH, et al. Sci Adv. 2019 Mar 20;5(3):eaav0316. doi: 10.1126/sciadv.aav0316.
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