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KG-548

Chemical Structure : KG-548

CAS No.: 175205-09-1

KG-548 (KG548)

Catalog No.: PC-62366Not For Human Use, Lab Use Only.

KG-548 is an ARNT/TACC3 disruptor (IC50=25 uM) that selectively bind within the ARNT PAS (Per-ARNT-Sim) domain that recruits TACC3..

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

KG-548 is an ARNT/TACC3 disruptor (IC50=25 uM) that selectively bind within the ARNT PAS (Per-ARNT-Sim) domain that recruits TACC3.

Physicochemical Properties

M.Wt 282.15
Formula C9H4F6N4
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

5-[3,5-Bis(trifluoromethyl)phenyl]tetrazole

References

1. Guo Y, et al. ACS Chem Biol. 2013 Mar 15;8(3):626-35.

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