Catalog No.: PC-70354Not For Human Use, Lab Use Only.
KKL-35 is a small molecule inhibitor of trans-translation that has broad-spectrum antibiotic activity, inhibits the trans-translation tagging reaction with an IC50 of 0.9 uM.
KKL-35 is a small molecule inhibitor of trans-translation that has broad-spectrum antibiotic activity, inhibits the trans-translation tagging reaction with an IC50 of 0.9 uM.
KKL-35 exhibits broad-spectrum antibiotic activity, validating trans-translation as a target for drug development.
KKL-35 prevented growth of B. anthracis and M. smegmatis with MIC values ≤6 µM (<2 µg/mL).
