KME-3859 | IRAK4 inhibitor | Probechem Biochemicals

Chemical Structure : KME-3859

Catalog No.: PC-21202Not For Human Use, Lab Use Only.

KME-3859 is a potent, selective IRAK4 inhibitor with IC50 of 5 nM, 100-fold selective over IRAK1.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

KME-3859 is a potent, selective IRAK4 inhibitor with IC50 of 5 nM, 100-fold selective over IRAK1.

M.Wt	323.40
Formula	C18H21N5O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-6-(6-methoxyimidazo[1,2-a]pyridin-3-yl)-N-(piperidin-3-yl)pyridin-2-amine

1. Bennett J, et al. Blood. 2023 Sep 14;142(11):989-1007.