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KUNG29

Chemical Structure : KUNG29

CAS No.: 1887032-92-9

KUNG29 (KUNG-29;KUNG 29)

Catalog No.: PC-60159Not For Human Use, Lab Use Only.

A potent, selective Grp94 inhibitor with Kd of 0.2 uM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

A potent, selective Grp94 inhibitor with Kd of 0.2 uM; displays 40-fold selecticity over Hsp90α; induces the degradation of integrin α2 in MDA-MB-231 cells.

Physicochemical Properties

M.Wt 430.89
Formula C22H23ClN2O5
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Methyl 3-Chloro-2-(2-(1-(2-ethoxybenzyl)-1H-imidazol-2-yl)-ethyl)-4,6-dihydroxybenzoate

References

1. Crowley VM, et al. J Med Chem. 2016 Apr 14;59(7):3471-88.

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