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Chemical Structure : KUNG94
Catalog No.: PC-60156Not For Human Use, Lab Use Only.
A potent, selective Grp94 inhibitor with IC50 of 8 nM.
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A potent, selective Grp94 inhibitor with IC50 of 8 nM; displays 10-fold selecticity over Hsp90α; shows antiproliferative activity against RPMI8226 cells with Gi50 of 1.4 uM, reduces LRP6 levels and induces apoptosis.
| M.Wt | 363.388 | |
| Formula | C22H18FNO3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Khandelwal A, et al. ACS Med Chem Lett. 2017 Sep 1;8(10):1013-1018.
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