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Chemical Structure : Keap1-Nrf2 inhibitor 25
Catalog No.: PC-20558Not For Human Use, Lab Use Only.
Keap1-Nrf2 inhibitor 25 is a potent, orally bioavailable Keap1-Nrf2 protein-protein interaction (PPI) inhibitor with IC50 of 89 nM.
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Keap1-Nrf2 inhibitor 25 is a potent, orally bioavailable Keap1-Nrf2 protein-protein interaction (PPI) inhibitor with IC50 of 89 nM.
Keap1-Nrf2 inhibitor 25 (3-30 mg/kg p.o.) demonstrated dose-dependent manner for up-regulation of the antioxidant protein heme oxigenase-1 (HO-1) in rat kidneys.
| M.Wt | 383.46 | |
| Formula | C23H26FNO3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Kazuki Otake, et al. ACS Medicinal Chemistry Letter. April 7, 2023
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