Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : L-733060
Catalog No.: PC-70193Not For Human Use, Lab Use Only.
An orally active, non-peptide, selective antagonist for the NK1 receptor with Ki of 0.8 nM.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
An orally active, non-peptide, selective antagonist for the NK1 receptor with Ki of 0.8 nM; inhibits neurogenic plasma extravasation in rat dura produced by electrical stimulation of trigeminal nerves with ID50 of 212 mg/kg, i.v., shows no effect on mean arterial blood pressure or heart rate in conscious or anaesthetised rats
| M.Wt | 403.361 | |
| Formula | C20H19F6NO | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Seabrook GR, et al. Eur J Pharmacol. 1996 Dec 12;317(1):129-35.
2. Rupniak NM, et al. Pain. 1996 Sep;67(1):189-95.
3. Rupniak NM, et al. Neuropharmacology. 2000 Jun 8;39(8):1413-21.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
