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L-Stepholidine

Chemical Structure : L-Stepholidine

CAS No.: 16562-13-3

L-Stepholidine (Stepholidine;(-)-Stepholidine;L-SPD)

Catalog No.: PC-45236Not For Human Use, Lab Use Only.

A protoberberine alkaloid that acts as a dual D2 receptor antagonist and D1 receptor agonist.

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Biological Activity

A protoberberine alkaloid that acts as a dual D2 receptor antagonist and D1 receptor agonist; has shown antipsychotic activity in animal studies.

Physicochemical Properties

M.Wt 327.3743
Formula C19H21NO4
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
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Solubility

10 mM in DMSO

Chemical Name/SMILES

6H-Dibenzo[a,g]quinolizine-2,10-diol, 5,8,13,13a-tetrahydro-3,9-dimethoxy-, (13aS)-

References

1. Natesan S, et al. Psychopharmacology (Berl). 2008 Aug;199(2):275-89.

2. Jin GZ, et al. Trends Pharmacol Sci. 2002 Jan;23(1):4-7.

3. Fu W, et al. Biophys J. 2007 Sep 1;93(5):1431-41.

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